Student Internship in Molecular Targeted Therapy (from January 2019, for 6-9 Months)

Job description

  Job facts

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are courageous in both decision and action. And we believe that good business means a better world.

That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Molecular Targeted Therapeutics (MTT) group located in Basel, Switzerland, is a Small Molecule Oncology group in the Oncology Discovery and Translation Area (DTA) of Roche Pharmaceutical Research and Early Development (pRED). This group has been built to deliver cutting edge therapeutics focusing on the discovery of novel targets, targeting mechanisms, and synthetic relationships in the area of cancer genomics, signal transduction, and cancer relevant immunological targets.

During the internship you will:

·  Work closely with a Post-Doc who will act as a mentor
·  Perform tissue culture of cancer cells for use in molecular biology assays
·  Develop and perform assays to evaluate targets of interest for potential intervention using small molecules
·  Interrogate and characterize pathway changes that occur with knockdown or pharmacologic inhibition of the target and study how those changes relate to biological outcome
·  Analyze data and present results in a large group to your colleagues

Your Profile

We are keen to discover talents who are passionate about learning and show great curiosity in discovering new things. At the Roche Headquarter site in Basel/Kaiseraugst, employees from over 90 countries are doing now what our patients need next. We contribute our share towards achieving our mission and to make our vision of personalized healthcare happen. We offer you a multicultural workplace in a modern environment, which at the same time requires you to be open-minded and adaptable. You provide us with examples that prove your ability to cultivate collaborations with different partners. This also means that you continuously contrast your results with others and acknowledge the benefit of collaboration and communications. As an intern you will join our Roche Interns Network that offers you chances to connect, have fun and get to know Basel, in the heart of Europe.

We are looking for a highly motivated Master Student who will work closely with the MTT biologists supported by Roche's Small Molecule Research (SMR). You are in the process of finishing your University studies in a science based field, including but not limited to biotechnology, biology, biochemistry, pharmacology, molecular biology and immunology. You can adapt to a fast paced, changing environment where challenges are seen as opportunities with an openness and a willingness to learn even in the face of such opportunities.

What do you need in your toolbox?

·  Experience in tissue culture and primary cell culture
·  Experience in a range of molecular biology techniques including western blotting, qPCR, cell proliferation assays
·  Hands-on experience with standard molecular biology methods including siRNA, shRNA, CRISPR/Cas9
·  Experience with basic cellular assays to test oncology-relevant therapeutics would be a plus
·  Familiarity with interrogation of bioinformatics databases
·  Understanding of basic protein biochemistry
·  Scientific engagement and desire to explore novel scientific and/or technical areas
·  Excellent presentation and communication skills
·  Fluent in written and oral English

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients' lives. If you want work in a passionate team, make your mark & improve lives, apply now.

The internship is available from January 2019. Please clearly mention your preferred start date and duration (6-9 months) and detail how your experience and personal attributes make you suitable for this role. Applications lacking a motivation letter will not be considered (please provide your motivation letter and CV as one document).

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Due to regulations non-EU/EFTA citizens have to provide a certificate from the university stating that an internship is mandatory as part of the application documents.

Roche strives to be an equal opportunity employer.

If you still have questions then please check our FAQs and videos on careers.roche.ch/faq .

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·  Who we are

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.